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发布于:2019-6-10 22:57:14  访问:60 次 回复:0 篇
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Manuscript Author Manuscript Author Manuscript Author ManuscriptCurr HIV/AIDS Rep. Author
General acceptability of PrEP was higher, specifically if it was produced available at no or little price and was highly effective [43]. Participants also discovered the need to have for routine HIV testing on a regular basis to be an acceptable practice [43]. Factors that would boost uptake and use of PrEP included practical access by means of health division clinics, pharmacies, or other venues that were conveniently accessible via public transportation [43]. Barriers to PrEP usage integrated potential side effects, high medication price, partial effectiveness, low perceived HIV danger, prospective unfavorable peer reactions, PF 750supplier burden connected having a everyday medication, beliefs that PrEP will be for MSM only, and concerns about possible increases in HIV threat behaviors as a type of threat compensation [43]. Two studies examined PrEP acceptability among HIV healthcare providers [44, 45]. Only 19 of these surveyed had prescribed PrEP, with all the majority prescribing PrEP to MSM and people s11671-016-1552-0 in serodiscordant relationships [44]. Providers noted issues linked with ARV resistance and poor adherence in conjunction with the prospective for elevated engagement in HIV getRG-14355 danger behaviors [44]. Inside a second mixed-methods study of Italian HIV healthcare specialists, providers noted quite a few issues including duration of PrEP use, potential unwanted side effects and toxicity, ARV resistance, troubles monitoring adherence, and the possibility s12917-016-0794-5 of increased prevalence of other STIs [45]. Furthermore, providers noted issues that funding for PrEP could adversely have an effect on the availability of funds for HIV-infected people applying ARVs [45]. Providers disagreed about the optimal population for PrEP, but suggested that HIV-uninfected folks in serodiscordant couples could be a important target population in lieu of people reporting high prices of sexual danger behavior simply because of fears of improved risk compensation [45]. Quantitative findings indicated that 30 would not prescribe PrEP; amongst these expressing a willingness to consider prescribing PrEP, 81 would give PrEP to at-risk men and women CEG.S111693 below some situations and 93 would prescribe to serodiscordant partners [45]. Providers also endorsed greater acceptability for HIV prevention solutions apart from PrEP which includes greater HIV testing access, HIV care, and behavioral HIV prevention interventi.Manuscript Author Manuscript Author Manuscript Author ManuscriptCurr HIV/AIDS Rep. Author manuscript; offered in PMC 2015 December 01.Brown et al.Pagebe acceptable to 85.9 with the sample [41]. In multivariate analyses, correlates of PrEP acceptability incorporated possessing a social network supportive of PrEP and possessing a history of prior sex with female sex workers [41]. 1 study examined the association in between HIV threat behavior engagement, perceived HIV risk, and PrEP interest among a sample of African Americans attending an STI clinic [42]. Taking a single dose ahead of sex was probably the most acceptable kind of PrEP (77 ), followed by a weekly PrEP dosage (76 ) and taking a single dose 1 day prior to sex (75 ); a day-to-day PrEP dosage was least acceptable (63 ) [42]. Additional, participants indicated decreased PrEP interest on account of present safer sex practices, concerns about unwanted effects, and likelihood for low adherence [42]. 20 also indicated they would use condoms significantly less frequently if taking PrEP and 7 reported they wouldn‘t use condoms at all if taking PrEP [42].
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