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Will likely be submitted as a peer-reviewed publication.Competing interests MB and
6Medizinische Abteilung, Novartis Pharma GmbH, N nberg, Germany. 7Berliner Behandlungszentrum der Abteilung f Psychiatrie, Psychotherapie und Psychosomatik, Evangelisches Krankenhaus K igin Elisabeth Herzberge gGmbH, Berlin, Germany. 8Institut f Klinische Pharmakologie, Medizinische Fakult , Technische Universit Carl Gustav Carus Dresden, Dresden, Germany. Received: 27 Could 2013 Accepted: 16 December 2013 Published: 19 December18.19. 20. 21. 22. 23. 24.25.26. References 1. Wang T, Bray SM, Warren ST: New perspectives around the biology of fragile X syndrome. Curr Opin Genet Dev 2012, 22(three):256?63. 2. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26024392 de Vries BB, PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28945807 Mohkamsing S, van den Ouweland AM, Mol E, Gelsema K, van Rijn M, Tibben A, Halley DJ, Duivenvoorden HJ, Oostra BA, et al: CS-5807 Screening for the fragile X syndrome amongst the mentally retarded: a clinical study. The collaborative fragile X study group. J Med Genet 1999, 36(six):467?70. three. Carter MT, Scherer SW: Autism spectrum disorder within the genetics clinic: a CS-5807 critique. Clin Genet 2013, 83(five):399?07. 4. Lewis P, Abbeduto L, Murphy M, Richmond E, Giles N, Bruno L, Schroeder S: Cognitive, language and social-cognitive capabilities of folks with fragile X syndrome with and with no autism. J Intellect Disabil Res 2006, 50(Pt 7):532?45. five. Barnes E, Roberts J, Extended SH, Martin GE, Berni MC, Mandulak KC, Sideris J: Phonological accuracy and intelligibility in connected speech of boys with fragile X syndrome or Down syndrome. J Speech Lang Hear Res 2009, 52(four):1048?061. six. Deshpande PS, Coffey DB: Fragile X syndrome and attention-deficit/ hyperactivity disorder symptoms. J Child Adolesc Psychopharmacol 2011, 21(six):639?42. 7. Baker JK, Seltzer MM, Greenberg JS: Behaviour challenges, maternal internalising symptoms and family members relations in families of adolescents and adults with fragile X syndrome. J Intellect Disabil Res 2012, 56(ten):984?95.Will likely be submitted as a peer-reviewed publication.Competing interests MB and HS are full-time workers of Novartis Pharma GmbH, N nberg, Germany. The other authors have received honoraria from Novartis Pharma, N nberg, for serving on the advisory board of this study, on the Novartis speakers‘ bureau, or for research projects connected to FXS. They declare no other competing interest. Authors‘ contributions All authors made substantial contributions to the style and coordination in the study. FH, DP, HS, and MB wrote the protocol. DP and FH wrote the initial draft in the primary text, and all authors authorized the final version to be published. Acknowledgement The authors acknowledge language editing by Claudia S. Copeland, PhD, New Orleans, USA.Haessler et al. BMC Psychiatry 2013, 13:339 http://www.biomedcentral.com/1471-244X/13/Page five ofAuthor information 1 Zentrum f Nervenheilkunde, Klinik f Psychiatrie, Neurologie, Psychosomatik und Psychotherapie im Kindes- und Jugendalter, Universit smedizin Rostock, Rostock, Germany. 2Abt. Psychiatrische Therapie f Menschen mit Geistiger Behinderung, Isar-Amper-Klinikum gGmbH, Klinikum M chen-Ost, Haar, Germany. 3Experimental and Clinical Study Center, Charit??Campus Berlin Buch Department of Psychiatry and Psychotherapy, Charit??Campus Mitte, Berlin, Germany. four Rheinhessen-Fachklinik Mainz, Kinder- und Jugendpsychiatrie, Mainz, Germany. 5St t. Krankenhaus Dresden-Neustadt, Zentrum f Kinder- und Jugendmedizin - Sozialp iatrisches Zentrum, Dresden, Germany.
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